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Experienced cell biologist specialising in process optimisation and standardisation, Biobanking, cellular reprogramming into stem cells (iPSCs) and differentiation.

Dr Chukwuma Agu , Cambridge, United Kingdom


Experience

15 - 24 years

Other titles

Principal Scientist Head of Stem Cell Facility Senior Staff Scientist Team Leader

Skills

SOPs LIMS Biochemistry Biotechnology Genotyping + 14 more

I'm offering


Markets

United Kingdom
United States
Germany
Netherlands
Denmark
Norway
Sweden
Finland
Lithuania

Links for more

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Language

German
Fluently
English
Fluently

Ready for

  Smaller project
  Larger project
  Ongoing relation / part-time
  Full time contractor

Available

Typically available right away

My experience

2019 - 2019   job
Principal Scientist Mogrify Ltd Cambridge.

2016 - 2019   job
Head of Stem Cell Facility unknown.
• Set up the stem cell facility including design, equipment and personnel.
• Managed a team of eight staff providing both daily direction and performance assessment
• Developed standard operating procedures (SOPs) for the derivation and maintenance and banking of induced
pluripotent stem cell lines (iPSCs), ensuring the best practices of biomanufacturing processes
• Implemented workflows to enable cost-effective, and efficient manufacturing of iPSCs
• Developed protocols for terminal differentiation of iPSC into red blood cells and cortical neurons
• Implemented quality control (QC) of stem cells such as trilineage differentiation, SNP array-based genotyping, cell
line identification (STR), mycoplasma tests.
• Ensured all facility certifications including ethics and licenses certifications were implemented thus ensuring
proper accreditation which was essential to maintaining operations
• Managed day-to-day facility operations, including budget, lab operations, infrastructure support, and vendor
management.
• Designed process maps, and implemented Laboratory Information Management System (LIMS) for sample
tracking
• Organised stem cell workshop and training programs both for academic and industrial users.
Design, Training, Budget, Management, Banking, Support, Information Management, Infrastructure, Assessment, Direction, Workshop, QC, Processes, UP

2012 - 2016   job
Senior Staff Scientist/Manager at Wellcome Trust Sanger Institute Cambridge CGaP.
Team Leader R&D Pipeline at CGaP facility at the Wellcome Trust Sanger Institute Cambridge
November /2013- July 2016
• Set up the R&D team and managed 5 full time scientists
• Created and implemented SOPs ensuring its adherence
• Optimised and implemented workflow for efficient manufacturing of iPSCs
• Transferred and adapted academic protocols into operational routine application, including scalability and Standardisation

Senior Scientific Manager: Team Leader IPSC Pipeline: CGaP facility at the Wellcome Trust Sanger Institute Cambridge
September 2012 - October 2013

• Involved in setting up the CGaP stem cell facility
• Recruited and managed 6 full time scientists.
• Provided scientific guidance and training on iPSC generation, expansion, quality control, and banking
• Ensured cell culture media, supplements and reagents are evaluated prior use for stem cell culture
• Created and implemented SOPS, risk assessments and process maps for iPSC derivation ensuring
adherence.
• The facility has produced and banked over 600 human-induced pluripotent stem cells available for purchase at ECAAC
and EBiSC.



1
R, Workflow, Sanger, Scalability, UP


My education

2002 - 2005
University of Vienna
PhD, Microbiology
• Evaluated the therapeutic property of bacteriophage lambda Holin on cancer cells using in vitro and in vivo methods.
• Demonstrated for the first time that Holin is cytotoxic to cancer cells in vitro and in animal models and characterised the potential mode of cell death.

1993 - 2000
University of Vienna
BSc/MSc, Microbiology


My resume

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